Understanding how cancer evolves is the key to stopping it

We started this blog as a means to talk to non-scientists about biology, and since we’re a group of evolutionary biologist, to talk mostly about evolutionary biology. My first post (oh those long years ago) was about Evolutionary Medicine. So imagine my delight with this recent article in the Atlantic addresses about how understanding evolution helps treat cancer. I don’t think I need to say this is awesome, but just in case… this is awesome.

Read about it here!

1920.jpg

Gut Microbes are Important for Cancer Treatment

We have written so much about the rapidly expanding study of human microbiomes, I don’t think I need to point them all out (but if you want to check them out, try here, here, here, here and here).

Well, it turns out understanding the human microbiome is important for one more thing. Fighting cancer.

Two independent research teams have demonstrated that gut microbes can dramatically alter the immune system’s ability to deal with cancer (in mice). This includes 1) an individual’s natural immunity to cancer and 2) how well they respond to immunotherapy cancer drugs.

Read about it over at the Atlantic!

lead_960

 

 

Going Viral Against Cancer

We have heard of viruses causing cancer (HPV) or even cancers that act like viruses (devil facial tumor virus).

But now there is a virus that can fight cancer! An engineered herpevirus provokes an immune response against cancer. And after a long hard road, it has been approved to treat certain types of cancer by the FDA!

Read about it over at Nature!

Killer T cells (orange) are recruited to attack malignant cells (mauve) in the viral-based cancer therapy T-VEC.

Killer T cells (orange) are recruited to attack malignant cells (mauve) in the viral-based cancer therapy T-VEC.