I am rarely aware of what the date is. Along with struggling to remember which is “right” and “left” this is one of my most basic flaws.
So I’m almost never aware when it’s April Fool’s Day, and when I read the tweet from Richard Lenski:
I was fooled. I’ll admit it. But then I read the post, and realized, while hilarious, he was kidding.
See follow up post for confirmation. 30-years, 70,000 generations and we’re just scratching the surface.
“While overuse of antibiotics has been fingered as the driver of resistance to these drugs, the contribution of bacterial sex plays an underappreciated role, one that could bedevil efforts to fight antimicrobial resistance.”
Want to hear more about this sexy and interesting outcome of bacteria doing it*?
Read more here!
*I’m pretty sure that’s how the song goes:
Birds do it.
Bees do it.
Bacteria do it and it drives the evolution of resistance.
Evolutionary biology is full of puzzles, most of which have the form “Evolution by natural selection should produce X but yet we see Y. How come?” Examples include the surprisingly high frequency of sterile males, individuals that help unrelated individuals reproduce, and senescence. Resolving the puzzle usually involves figuring out why trait or behavior X actually is adaptive despite appearances to the contrary, as with individuals that help non-relatives reproduce.
What are the biggest puzzles in ecology? Does ecology have as many puzzles as evolutionary biology? And if not, does that indicate a failing of ecology?
Here’s a classic ecological puzzle: Hairston, Smith, and Slobodkin’s question, why is the world green? That is, why is the world covered with plants, given that there are lots of herbivores around that you’d think would eat all the plants?
Interested? Read more about the puzzles in Ecology and which ones are global and which ones are local, here!
The idea for the mother’s curse goes like this. Most human genes are on chromosomes, but a tiny number are in mitochondria, little power factories in human cells that for reasons of evolutionary history have their own loops of DNA. Sperm do not pass on any mitochondria, but eggs do. Therefore, all sons and daughters inherit their mitochondrial DNA from their mother (great mother’s day present idea: sequence yourmitochondria, make into cool figure, give it to your mom thanking her for the DNA). If a harmful mutation in mitochondrial DNA ends up in a woman, she will be less evolutionarily “fit” and thus less able to pass it along. But if the mutation ends up in a man, nothing happens. He never passes along mitochondrial DNA anyway.
However, this hasn’t been tested all that often in humans. Until a perfect system arose. You see, the first King’s Daughters—or filles du roi—arrived in New France in 1663, and 800 more would follow over the next decade. They were poor and usually of common birth, but their passage and dowry were indeed paid by King Louis XIV for the purpose of empire building: These women were to marry male colonists and have many children, thus strengthening France’s hold on North America. And so they did.
One of these is Leber’s hereditary optic neuropathy, which causes vision loss, usually in young men. Recently, geneticists using French Canadian genealogy have reexamined the effects of Leber’s and found a striking pattern of inheritance: It seems to show a long-theorized but never-seen-in-humans pattern called the “mother’s curse.”
Want to know more? Read about it here.
It is the height of arrogance for industrialized countries to demand that developing countries conserve nature, while they plowed down natural resources (and often still do) to gain economic supremacy.
And that sentiment is reflected in a recent piece about the 18th anniversary of the death of Michael Werikhe, the enigmatic African conservationist.
Moreover, some of these points were emphasized in an interesting stream over on twitter.
The first step is recognizing the problem. But how do we solve said problem?
The great things about CRISPR is its potential do all kinds of interesting things! The scary part about CRISPR is its ability to mutate human embryos and the slippery slope to designer babies. That last part might be an exaggeration… but given that scientists just removed a dangerous mutation from human embryos…. its not too far off.
You can read about it all over the place, but I particularly like this NY Times article.
Embryos before and after editing.