The Complicated Legacy of the Mad Scientist

When I was around ten years old, I dressed up as a mad scientist for Halloween. I wore coke-bottle glasses and a lab coat splattered with a mysterious green substance. I carried a (fake) lab rat in my pocket, along with test tubes full of brightly colored solutions. And my mom did my hair, using a comb and A LOT of white hairspray to give me a look that I hoped was reminiscent of Doc Brown (but that probably looked more like Beetlejuice).

I have been fascinated by the mad scientist for as long as I can remember. Growing up, my favorite television shows included Pinky and the Brain, Beakman’s World, and Mystery Science Theater 3000. I loved Back to the Future, and I watched Batman Forever over and over again to see Jim Carrey play Edward Nygma.


Doc Brown in Back to the Future

Once I got a little older, I was able to appreciate some of the more sinister mad scientists in cinematic and literary history; characters like Dr. Moreau, Dr. Seth Brundle, and, of course, Dr. Victor Frankenstein. The mad scientists of movies and books helped to nurture my interest in the natural world, capturing my imagination in ways that the standard, garden-variety scientist sometimes did not.

Though an important and positive part of my childhood, the legacy of the mad scientist is actually quite complicated. The mad scientist archetype has grown out of society’s simultaneous fascination with, and fear of, scientific discovery, and thus it has had both positive and negative effects on the public perception of science.

The good: mad scientists are creative and exciting

One great thing about mad scientists as fictional characters is that they help keep the public engaged in science. Science is commonly perceived as boring. Scientists are generally thought of as generic and unsmiling (even by scientists themselves!) and science is seen as a mind-numbingly mundane process. Mad scientists, in contrast, are anything but boring. The mad scientist is an engaging character that tends to shake things up- when a mad scientist is on the scene, you know things are about to get interesting (and probably a little bit weird, too).

Another positive of mad scientists is that they help to dispel the myth that science is not creative. Science is often viewed as the antithesis of art: people who are good at science aren’t creative, and people who are creative can’t hack it at science. This misconception is particularly frustrating given that successful science actually requires a good deal of ingenuity and innovation. Mad scientists aren’t afraid to think outside the box- in fact, this is one of the hallmarks of their madness. They push the boundaries of scientific discovery, with sometimes spectacular, and sometimes disastrous, results.

The bad: mad scientists are eccentric, greedy, and immoral

The mad scientist has also done a fair amount to negatively impact the public perception of science. In fact, some of the most common misconceptions surrounding present-day scientists share apparent connections with the mad scientist archetype.

For instance, even the most benign mad scientists in fiction are often portrayed as zany and peculiar. Their laboratories are full of ridiculous rube goldberg-esque inventions, and they spend time developing elaborate and impractical schemes to solve trivial problems. Characters with these qualities include Back to the Future’s Doc Brown and Futurama’s Professor Farnsworth. At first glance, this trope may seem fairly harmless to scientists in the real world. However, politicians like Representative Lamar Smith routinely rely on this trope to argue against government support of academic research, citing seemingly obscure-sounding NSF-funded projects in order to make scientists sound eccentric and irresponsible.

Another common characteristic of mad scientists is that they are doing mad science for some kind of personal gain. Alchemists in 15th century fiction were commonly depicted as being motivated by greed, while comic super villains such as Lex Luthor and Doctor Doom are often in pursuit of power and control. And in this summer’s Jurrasic World, Dr. Wu got the mad scientist treatment when we found out he was creating genetically enhanced super-dinos for the US military, for profit. In the real world, this trope is particularly relevant to the climate change debate. Climate change deniers, seeking to undermine experts in the field, often argue that the researchers have fabricated results in order to increase job security and funding.

Finally, mad scientists in books and movies are frequently portrayed as having a corruptive influence on society. The scientist’s research is itself in direct conflict with morality, resulting in harm to the scientist and those around him. For example, Dr. Victor Frankenstein, Nathan from Ex Machina, and the creator of the Replicants in Blade Runner are all scientists that pursued taboo work, with disturbing results. In the real world, some of the most direct effects of this trope can be seen in the field of evolutionary biology. Evolutionary theory is thought by many to encourage immoral behavior, and this viewpoint is common enough that it continues to affect science education in schools throughout the US.

The future: Princess Bubblegum and diversity in the mad sciences

Mad scientists are exciting and creative. They are also often eccentric, greedy, and morally misguided. The mad scientist’s ambiguity is one of the things that makes him such a compelling character, but the negative characteristics of fictional scientists can have very real consequences for scientists and science educators.

Today, we are entering a new age in the world of the mad scientist. My proof? Princess Bubblegum, of the animated television series Adventure Time.

Princess Bubblegum is a fantastically unique and incredibly interesting character. She isn’t your typical mad scientist- she’s a she, for starters, and she’s a princess! She’s smart, curious, and morally ambiguous. Her science often falls more on the “mad” side of the spectrum. For instance, in an experiment gone wrong she created the Earl of Lemongrab, a lemon-headed creature who terrorizes and cannibalizes the inhabitants of his earldom. So yeah, definitely some mad science going on there.

Princess Bubblegum, doing science

Princess Bubblegum introduces some diversity into the incredibly one-dimensional world of the mad scientist. And her arrival on the mad scientist scene comes at a time when our perception of scientists in the real world is experiencing an overhaul as well.

Historically, we as a society have had a very narrow definition of what it means to be a scientist. Scientists have traditionally been pictured as straight white males, and also as “lone geniuses”- socially isolated, naturally gifted individuals that exhibit a dedication to their work that borders on obsession. In other words, what we commonly think of as the “ideal” scientist is essentially just the archetypal mad scientist, minus the bad hair day. Really, is it any surprise that the line between scientist and mad scientist can sometimes seem so blurry?

Fortunately, we are beginning to move away from this one-dimensional view of what makes a scientist a scientist. Thanks to recent campaigns highlighting diversity in STEM fields, greater recognition that scientific progress tends to be collaborative in nature (rather than the work of a single “genius”), and a push to address the shockingly pervasive “culture of acceptance” surrounding mental health problems in academia, we are closer than ever to dispelling the myth that only certain people belong in the sciences.

As we continue to achieve greater levels of diversity in the sciences, I hope that we also continue to broaden our horizons with depictions of mad scientists in fiction. And as the motivations, backstories, and personality traits of these characters become more varied, the outdated tropes of the archetypal mad scientist will inform our perceptions of real scientists less and less.

So here’s looking forward to mad scientists that shake things up, that break the mold, that play by their own rules push the boundaries of what we already know. Because, really, isn’t that what the mad scientist is all about?

And in honor of the upcoming holiday, please check out our compilation of some of the greatest mad scientists in cinematic history. Happy Halloween!

Why the Elephant Didn’t get Cancer:

Follow my logic here: cancer occurs due to mutations in your cells. Elephants have A LOT more cells than people do. Therefore, elephants should have more cancer than people.

But they don’t. In fact, elephants have one of the lowest cancer mortality rates in the animal kingdom.

And scientist (at Huntsman Cancer Institute, University of Utah School of Medicine, and Primary Children’s Hospital) have figured out the answer.

p53 heatshock proteins, known in some circles as the “Guardian of the Genome” (soon to be a Marvel movie I’m sure), are one of the key tumor suppressing genes. Humans have 2 genes for p53 proteins. Elephants have 38.

Read about it over at Slate!


The controversy over a kingfisher

Over at Huffington Post, Marc Bekoff, recently wrote an article lambasting Christopher Filardi for collecting a Moustached Kingfisher, a rare bird endemic in the Solomon Islands.

Now, there are two sides to this particular controversy, and I am going to do my darnest NOT to pick one.

Side one: How dare you kill that kingfisher!

The HP article criticized killing a rare bird for collection as the opposite of a conservation effort. It is likened to hunting endangered species, and  compassionate conservation. (RadioLab anyone? Don’t mind if I do…)

Side two: You need these kinds of specimen for conservation. And biology. 

An excellent public post was written by my friend Josef Uyeda here.

Additionally, Dr. Filardi himself responded justifying his decision, and why specimens are important over at the Audobon society.

Was it right or was it wrong? You decide.

Holding kingfisher II.jpg.CROP.promovar-mediumlarge



Cards against humanity, for humanity!

You know that card game that makes you giggle inappropriately? Well, it turns out the company behind them is not as bad as one would think.

This year the gaming company announced it would be selling a science related expansion pack. And all the proceeds from this pack? They go towards four-year scholarships for women pursuing undergraduate degrees in STEM fields.

For a company geared toward “horrible” people, Cards Against Humanity sure does do some pretty meaningful things.

Read about it over at Huffington Post.

And get out there and support women in STEM.


Riding a Bike for Antibiotic Resistance Awareness

In 6 months, my friend Wesley Loftie-Eaton will cycle from Nairobi (Kenya) to Cape Town (South Africa). This epic trip is not only for the sake of adventure, but to raise awareness on antibiotic resistance and promote research in Africa. The first three blogs are already up and they are titled “Why cycling?“, “Why Antibiotic Action?” and “Why science in Africa?”.
A successful mission depends on promotion, so like, share, donate, subscribe, etc., to help Wesley in this important campaign.

His blog is here, go check it out!



23andMe will resume (some) genetic health testing


(Flickr: Nathan Nelson)

Via the New York Times, it looks like the home genotyping company 23andMe is getting the go-ahead from the US Food and Drug Administration to give customers medical information linked to their personal genetics. But not just any medical information:

The new health-related information 23andMe will provide is called carrier status. That relates to whether people have genetic mutations that could lead to a disease in their offspring, presuming the other parent has a mutation in the same gene and the child inherits both mutated genes. There will be information on 36 diseases, including cystic fibrosis, sickle cell anemia and Tay-Sachs.

Continue reading

Reading list recommendations from your favorite scientists

Over at IFLS they have posted a list of books that Neil deGrasse Tyson thinks everyone should read.

The Bible“: “To learn that it’s easier to be told by others what to think and believe than it is to think for yourself.”

The System of the World” by Isaac Newton: “To learn that the universe is a knowable place.”

On the Origins of Species” by Charles Darwin: “To learn of our kinship with all other life on Earth.”

Gulliver’s Travels” by Jonathan Swift: “To learn, among other satirical lessons, that most of the time humans are Yahoos.”

The Age of Reason” by Thomas Paine: “To learn how the power of rational thought is the primary source of freedom in the world.”

The Wealth of Nations” by Adam Smith: “To learn that capitalism is an economy of greed, a force of nature unto itself.”

The Art of War” by Sun Tzu: “To learn that the act of killing fellow humans can be raised to an art.”

The Prince” by Niccolo Machiavelli: “To learn that people not in power will do all they can to acquire it, and people in power will do all they can to keep it.”

All based off a reddit post from 2011.


Followed by interesting titles by other scientist you may know and love:

Jane Goodall: “Animal Liberation” by Peter Singer

Michio Kaku: “The Foundation Trilogy” by Isaac Asimov

Oliver Sacks: “The Mind of a Mnemonist” by Aleksandr R. Luria

Steven Pinker: “1984” by George Orwell , “The Selfish Gene” by Richard Dawkins

Sean Carroll: “One, Two, Three…Infinity” by George Gamow

Steve Jones: “Farthest North” by Fridjtof Nansen

Jared Diamond: “Child of the Jungle” by Sabine Kuegler

Max Tegmark: “Permutation City” by Greg Egan

Adam Riess: “Contact” by Carl Sagan ,  “The Fountains of Paradise” by Arthur C. Clarke

Steven Strogatz: “The Andromeda Strain” by Michael Crichton

Ainissa Ramirez: “Parable of the Sower” by Octavia E. Butler

Sarah Blaffer Hrdy: “The Beak of the Finch” by Jonathan Weiner , “Genome: The Autobiography of a Species in 23 Chapters” by Matt Ridley

Melvin Konner: “Why Zebras Don’t Get Ulcers” by Robert M. Sapolsky  ,  “Descartes’ Error: Emotion, Reason, and the Human Brain” by Anthony Damasio

Keith Thomson: “The Fly in the Cathedral” by Brian Cathcart



Save the Parasites

No, I’m not kidding.

An excellent article over at the Atlantic makes a plea for conservation of parasites.

The author (Ed Yong) makes a plea for conservationist to stop discriminating against parasites, or worse, continually attempting to eradicate them.

Now, it’s hard to argue that parasites that are decimating human populations should be conserved. But there is a strong case that parasites can be vital to ecosystems and by removing them we are doing more harm then good. 

Read about it here.



An Emerging Parasite: Typanosoma cruzi

Kinetoplastida, is one of my favorite parasite classes. They are cool biologically (the kinetoplast, I’M TELLING YOU), and in terms of the extreme nature of the diseases they cause.

And one that has long held sway in Latin America is Chagas, a disease caused by Trypanosoma cruzi. The parasite is limited in it’s range because it requires a vector, Triatomine also known as the “kissing” bug.

However, with record high climate in North America, our little kissing arthropod is moving north and into the US!

Read about this emerging infectious disease over at Forbes!



It is no secret that I have a deep undying love for parasites.


And given that I keep running across awesome parasite things to post, this week I will dedicate all my posting to the glorious organisms that make it their lifes’ work to destroying yours.

Starting off with one of my favorite ever websites: Parasite of the Day.

From the rare, to the common to the exceedingly rare this website posts constantly about awesome parasites.

Check them out here, and stay tuned for the rest of this week of glorious GLORIOUS parasites.