The Body’s Ecosystem is a comprehensive – yet short enough to finish in a single sitting – review on current NON-GUT microbiota research, focusing on the mouth, lungs, swimsuit area, maternal microbiome and skin. It’s pretty interesting and pretty pretty – I really liked the accompanying artwork (including two hand-drawn, possibly NSFW genitalia pictures). It also features research from a couple UIdaho labs (m’ alma mater). In other words, a darn good read, in my opinion.
Altogether, the members of the human body’s microbial ecosystem make up anywhere from two to six pounds of a 200-pound adult’s total body weight, according to estimates from the Human Microbiome Project, launched in 2007 by the National Institutes of Health (NIH). The gastrointestinal tract is home to an overwhelming majority of these microbes, and, correspondingly, has attracted the most interest from the research community. But scientists are learning ever more about the microbiomes that inhabit parts of the body outside the gut, and they’re finding that these communities are likely just as important. Strong patterns, along with high diversity and variation across and within individuals, are recurring themes in microbiome research. While surveys of the body’s microbial communities continue, the field is also entering a second stage of inquiry: a quest to understand how the human microbiome promotes health or permits disease.